More than one company is trying to take advantage of the potential benefits of spermidine, a compound that is currently capturing the attention of longevity experts. One such company is Oxford Healthspan, which recently launched its innovative Primeadine product (https://longevity.technology/lifestyle/oxford-healthspan-primeadine-spermidine-review-a-revolutionary-approach-to-holistic-aging/).
Primeadine features spermidine as its primary ingredient, and it has a powerful impact on our metabolism. It has also been used to try to encourage autophagy, the process through which our bodies clean out any damaged or unnecessary cells to ensure we’re functioning at our best. Other possible advantages to spermidine supplements under investigation include protecting the heart, regulating hormones, improving cognition and even helping hair and nails grow to be healthy and beautiful.
The spermidine in Primeadine is sourced entirely from food, specifically Japanese wheat germ extract. Japan is a country that is famous for the longevity of its citizens, so we know they’re getting something right over there. This wheat germ, delivered in 900g doses, is then processed in the US, where it is combined with two other powerful ingredients, spermine and putrescine, both of which encourage the body to produce more spermidine. Another addition is the fiber FOS, which is extracted from the maltodextrin found in beets and can boost bacteria that create spermidine in the gut.
Ensuring that Primeadine is only sourced from natural ingredients will provide reassurance to many consumers. It also improves bioavailability, or how the body processes and makes use of the spermidine in the most effective way. It’s also vegan-friendly and has been adapted to have a gluten-free version. Users can also be reassured that not only does it have scientific backing, but it’s also designed to comply with regulators in both the US and Japan.
A wheat-germ-based supplement isn’t going to be suitable for all people, particularly those with celiac disease or other digestive issues. This also means that you need to introduce the supplement slowly; you can’t go straight to the maximum dose, which may be annoying. You start with one capsule, then increase to two and later three, all of which need to be taken with a liquid at meal times.
It may not be the easiest and most convenient way to take a supplement, and it’s not for everyone, but for people who can safely take Primeadine, there could be a wide range of benefits.